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Director/Sr. Director, Therapeutic Antibody Discovery
at
Mab-Venture Biopharma
in Shanghai
职责包括但不限于以下各项：
1) Select tractable molecular targets with excellent biological rationale for the therapeutic antibody discovery project teams across multiple disease areas;
2) Lead the project teams to establish high-throughput and robust functional assays for lead antibody screening;
3) Drive department-wide efforts to isolate, clone, engineer, and optimize new biologic entities with excellent in vitro and in vivo biological functions and developability using a variety of technologies;
4) Support CMC development and IND-enabling studies for lead candidates.
任职要求：
1) Ph.D. with at least 10 years of working experience in Oncology, Immunology, Biochemistry, Molecular and Structural Biology or related discipline;
2) Prior experience leading therapeutic antibody discovery projects and managing project team(s), industry experience from overseas strongly preferred;
3) Familiarity with antibody structure, properties and sequences;
3) Prior experience in the design, execution, and analysis of immunological, biochemical, and/or cellular assays (e.g., ELISA, ELISPOT, FCM, Western blot, immunoprecipitation, MLR, etc.) and assay results;
4) Expertise utilizing techniques for antibody structure modeling, engineering, humanization, affinity measurement and affinity maturation;
5) Ability to demonstrate autonomy, good judgement and inspiration of others;
6) Ability to set aggressive goals and clear direction and to measure performance for the project team(s);
7) Excellent written and verbal communication skills in both English and Mandarin.
1) Select tractable molecular targets with excellent biological rationale for the therapeutic antibody discovery project teams across multiple disease areas;
2) Lead the project teams to establish high-throughput and robust functional assays for lead antibody screening;
3) Drive department-wide efforts to isolate, clone, engineer, and optimize new biologic entities with excellent in vitro and in vivo biological functions and developability using a variety of technologies;
4) Support CMC development and IND-enabling studies for lead candidates.
任职要求：
1) Ph.D. with at least 10 years of working experience in Oncology, Immunology, Biochemistry, Molecular and Structural Biology or related discipline;
2) Prior experience leading therapeutic antibody discovery projects and managing project team(s), industry experience from overseas strongly preferred;
3) Familiarity with antibody structure, properties and sequences;
3) Prior experience in the design, execution, and analysis of immunological, biochemical, and/or cellular assays (e.g., ELISA, ELISPOT, FCM, Western blot, immunoprecipitation, MLR, etc.) and assay results;
4) Expertise utilizing techniques for antibody structure modeling, engineering, humanization, affinity measurement and affinity maturation;
5) Ability to demonstrate autonomy, good judgement and inspiration of others;
6) Ability to set aggressive goals and clear direction and to measure performance for the project team(s);
7) Excellent written and verbal communication skills in both English and Mandarin.
Published at 20-Sep-2017
Viewed: 4800 times
Viewed: 4800 times